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YHI9 Yhi9p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856424, updated on 24-Jan-2026
Official Symbol
YHI9
Official Full Name
Yhi9p
Primary source
SGD:S000001071
Locus tag
YHR029C
See related
AllianceGenome:SGD:S000001071; FungiDB:YHR029C; VEuPathDB:YHR029C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable isomerase activity. Involved in endoplasmic reticulum unfolded protein response. Located in chromatin. Orthologous to human PBLD (phenazine biosynthesis like protein domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See YHI9 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (167677..168561, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene proteasome regulatory particle base subunit RPN1 Neighboring gene dipeptidyl aminopeptidase Neighboring gene mitogen-activated serine/threonine-protein kinase SLT2 Neighboring gene DNA helicase

Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily. Liger D, et al. Proteins, 2005 Sep 1. PMID 16021630
  2. Genomic analysis of the Opi- phenotype. Hancock LC, et al. Genetics, 2006 Jun. PMID 16582425, Free PMC Article
  3. Discovery and identification of genes involved in DNA damage repair in yeast. Jagadeesan SK, et al. Gene, 2022 Jul 15. PMID 35569766
  4. APEX2-mediated proximity labeling resolves protein networks in Saccharomyces cerevisiae cells. Singer-Krüger B, et al. FEBS J, 2020 Jan. PMID 31323700
  5. Analysis of the vacuolar luminal proteome of Saccharomyces cerevisiae. Sarry JE, et al. FEBS J, 2007 Aug. PMID 17651441

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. YHI9 has a fold similar to bacterial diaminopimelate epimerase, revealing a bimodular structure with an internal symmetry
    Title: Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chromatin IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
Yhi9p
NP_011894.1
  • hypothetical protein; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    167677..168561 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179159.1 → NP_011894.1  Yhi9p

    See identical proteins and their annotated locations for NP_011894.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKX6, P38765
    UniProtKB/TrEMBL
    A6ZST5, B3LSF0, B5VJW0, C7GTV1, C8ZA97, N1P1J3
    Conserved Domains (1) summary
    TIGR00654
    Location:3 → 294
    PhzF_family; phenazine biosynthesis protein PhzF family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38765.1

Gene LinkOut

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