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ARD1 peptide alpha-N-acetyltransferase complex A subunit ARD1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856404, updated on 5-Sep-2021

Summary

Gene symbol
ARD1
Gene description
peptide alpha-N-acetyltransferase complex A subunit ARD1
Primary source
SGD:S000001055
Locus tag
YHR013C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
NAA10
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Genomic context

See ARD1 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (130730..131446, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene putative serine--tRNA ligase DIA4 Neighboring gene retromer subunit VPS29 Neighboring gene Spo13p Neighboring gene tRNA

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the ARD1 gene: The ARD1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, and rice.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to peptide alpha-N-acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables peptide alpha-N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
contributes_to peptide alpha-N-acetyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables peptide-glutamate-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables peptide-serine-N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NatA complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of NatA complex IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
peptide alpha-N-acetyltransferase complex A subunit ARD1
NP_011877.1
  • Subunit of protein N-terminal acetyltransferase NatA; NatA comprises Nat1p, Ard1p, Nat5p; acetylates many proteins to influence telomeric silencing, cell cycle, heat-shock resistance, mating, sporulation, early stages of mitophagy; protein abundance increases under DNA replication stress; mutations in human homolog X-linked NAA10 lead to Ogden syndrome (S37P) and intellectual disability (R116W); expression of human NAA10 and NAA15 can complement ard1 nat1 double mutant

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    130730..131446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179143.1NP_011877.1  TPA: peptide alpha-N-acetyltransferase complex A subunit ARD1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011877.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P07347
    Conserved Domains (1) summary
    COG0456
    Location:1192
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
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