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SOD2 superoxide dismutase SOD2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856399, updated on 4-Nov-2018

Summary

Gene symbol
SOD2
Gene description
superoxide dismutase SOD2
Primary source
SGD:S000001050
Locus tag
YHR008C
Gene type
protein coding
RNA name
superoxide dismutase SOD2
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See SOD2 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (122889..123590, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene sterol 14-demethylase Neighboring gene hypothetical protein Neighboring gene Tda3p Neighboring gene ribosomal 60S subunit protein L27A

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the SOD2 gene: The SOD2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
superoxide dismutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
superoxide dismutase activity IDA
Inferred from Direct Assay
more info
PubMed 
superoxide dismutase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
age-dependent response to oxidative stress involved in chronological cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
age-dependent response to reactive oxygen species involved in chronological cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
aging IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
reactive oxygen species metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
removal of superoxide radicals IEA
Inferred from Electronic Annotation
more info
 
replicative cell aging IMP
Inferred from Mutant Phenotype
more info
PubMed 
superoxide metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
mitochondrion HDA PubMed 
mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
superoxide dismutase SOD2
NP_011872.1
  • Mitochondrial manganese superoxide dismutase; protects cells against oxygen toxicity and oxidative stress; human mitochondrial SOD2 can complement a yeast null mutant and human cytoplasmic SOD1 can also complement when targeted to the mitochondrial matrix

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    122889..123590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179138.1NP_011872.1  TPA: superoxide dismutase SOD2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011872.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P00447
    Conserved Domains (1) summary
    COG0605
    Location:25233
    SodA; Superoxide dismutase [Inorganic ion transport and metabolism]
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