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PZF1 Pzf1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856316, updated on 2-Nov-2024

Summary

Official Symbol
PZF1
Official Full Name
Pzf1p
Primary source
SGD:S000006390
Locus tag
YPR186C
See related
AllianceGenome:SGD:S000006390; FungiDB:YPR186C; VEuPathDB:YPR186C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TFC2
Summary
Enables RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity and RNA polymerase III type 1 promoter sequence-specific DNA binding activity. Involved in 5S class rRNA transcription by RNA polymerase III. Predicted to be located in nucleus. Orthologous to human GTF3A (general transcription factor IIIA). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See PZF1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (909733..911022, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene bifunctional 4-alpha-glucanotransferase/amylo-alpha-1,6-glucosidase Neighboring gene serine/threonine protein kinase regulatory subunit ATG13 Neighboring gene DNA-directed RNA polymerase core subunit RPO26 Neighboring gene Mlc2p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Process Evidence Code Pubs
involved_in 5S class rRNA transcription by RNA polymerase III IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IC
Inferred by Curator
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Pzf1p
NP_015512.1
  • Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    909733..911022 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184283.1NP_015512.1  TPA: Pzf1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015512.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4I6, P39933
    UniProtKB/TrEMBL
    B3LKE5, B5VTW6, C7GP68, C8ZJL5, N1NXW4
    Conserved Domains (2) summary
    COG5048
    Location:46427
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:5474
    ZF_C2H2; C2H2 Zn finger [structural motif]