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ASN1 asparagine synthase (glutamine-hydrolyzing) 1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856268, updated on 18-Jan-2023

Summary

Gene symbol
ASN1
Gene description
asparagine synthase (glutamine-hydrolyzing) 1
Primary source
SGD:S000006349
Locus tag
YPR145W
See related
AllianceGenome:SGD:S000006349
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables asparagine synthase (glutamine-hydrolyzing) activity. Involved in asparagine biosynthetic process. Located in cytoplasm. Orthologous to human ASNS (asparagine synthetase (glutamine-hydrolyzing)). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See ASN1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (822620..824338)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene ribosome biosynthesis protein NOC4 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene bifunctional triacylglycerol lipase/ester hydrolase

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables asparagine synthase (glutamine-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables asparagine synthase (glutamine-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables asparagine synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in L-asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in asparagine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in asparagine biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in organonitrogen compound metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
asparagine synthase (glutamine-hydrolyzing) 1
NP_015471.1
  • Asparagine synthetase; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway; ASN1 has a paralog, ASN2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    822620..824338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184242.1NP_015471.1  TPA: asparagine synthase (glutamine-hydrolyzing) 1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015471.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4E2, P49089
    UniProtKB/TrEMBL
    A0A0L8VG76, A0A6A5Q676, A0A6C1E260, A6ZX21, B3LKA5, B5VTT1, C7GXT2, C8ZJG8, G2WPV8, N1P2F7
    Conserved Domains (1) summary
    PRK09431
    Location:1562
    asnB; asparagine synthetase B; Provisional