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CTF4 chromatin-binding protein CTF4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856254, updated on 5-Sep-2021

Summary

Gene symbol
CTF4
Gene description
chromatin-binding protein CTF4
Primary source
SGD:S000006339
Locus tag
YPR135W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CHL15; POB1
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Genomic context

See CTF4 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (799234..802017)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Tom5p Neighboring gene Mss18p Neighboring gene Rrp9p Neighboring gene gag-pol fusion protein Neighboring gene gag protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the CTF4 gene: The CTF4 gene is conserved in S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, and N.crassa.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication initiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA-dependent DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA-dependent DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in double-strand break repair via break-induced replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in establishment of sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic sister chromatid cohesion IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in mitotic sister chromatid cohesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in nuclear replication fork IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nuclear replication fork IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of replication fork protection complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
chromatin-binding protein CTF4
NP_015461.1
  • Chromatin-associated protein; required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p); recruits Mms22p to replication forks during S phase, and may link DNA synthesis to sister chromatid cohesion

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    799234..802017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184232.1NP_015461.1  TPA: chromatin-binding protein CTF4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015461.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q01454
    Conserved Domains (3) summary
    sd00039
    Location:140176
    7WD40; WD40 repeat [structural motif]
    pfam12341
    Location:478779
    Mcl1_mid; Minichromosome loss protein, Mcl1, middle region
    cl29593
    Location:233347
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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