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LTP1 tyrosine protein phosphatase LTP1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856187, updated on 7-Jul-2024

Summary

Gene symbol
LTP1
Gene description
tyrosine protein phosphatase LTP1
Primary source
FungiDB:YPR073C
Locus tag
YPR073C
See related
SGD:S000006277; AllianceGenome:SGD:S000006277; VEuPathDB:YPR073C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein tyrosine phosphatase activity. Involved in protein dephosphorylation. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; diabetes mellitus (multiple); diabetic retinopathy; and obesity. Orthologous to human ACP1 (acid phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See LTP1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (691933..692418, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene tRNA-Ser Neighboring gene CCR4-NOT core subunit NOT5 Neighboring gene transketolase TKL1 Neighboring gene Opy2p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
tyrosine protein phosphatase LTP1
NP_015398.1
  • Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    691933..692418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184170.1NP_015398.1  TPA: tyrosine protein phosphatase LTP1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015398.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W477, P40347
    UniProtKB/TrEMBL
    A0A6A5Q335, A6ZWW0, B3LLC6, C7GXZ9, C8ZJ98, G2WPP5, N1NWD4
    Conserved Domains (1) summary
    cd00115
    Location:9158
    LMWP; Low molecular weight phosphatase family