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MED1 Med1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856183, updated on 8-May-2022

Summary

Gene symbol
MED1
Gene description
Med1p
Primary source
SGD:S000006274
Locus tag
YPR070W
See related
AllianceGenome:SGD:S000006274
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transcription coregulator activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Part of core mediator complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See MED1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (685898..687598)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene histone deacetylase Neighboring gene spermidine synthase Neighboring gene uncharacterized protein Neighboring gene tRNA-Ser

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of core mediator complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of mediator complex IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Med1p
NP_015395.1
  • Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    685898..687598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184167.1NP_015395.1  TPA: Med1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015395.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q12321
    Conserved Domains (1) summary
    pfam10744
    Location:12173
    Med1; Mediator of RNA polymerase II transcription subunit 1