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IDI1 isopentenyl-diphosphate delta-isomerase IDI1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855986, updated on 17-May-2024

Summary

Gene symbol
IDI1
Gene description
isopentenyl-diphosphate delta-isomerase IDI1
Primary source
FungiDB:YPL117C
Locus tag
YPL117C
See related
SGD:S000006038; AllianceGenome:SGD:S000006038; VEuPathDB:YPL117C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
BOT2; LPH10
Summary
Enables isopentenyl-diphosphate delta-isomerase activity. Involved in farnesyl diphosphate biosynthetic process. Located in cytosol and nucleus. Used to study cancer. Orthologous to several human genes including IDI2 (isopentenyl-diphosphate delta isomerase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See IDI1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (327864..328730, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene putative DEAD-box ATP-dependent RNA helicase DBP1 Neighboring gene mitochondrial 37S ribosomal protein MRP51 Neighboring gene histone deacetylase Neighboring gene GTPase-activating protein BEM3

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables isopentenyl-diphosphate delta-isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables isopentenyl-diphosphate delta-isomerase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables isopentenyl-diphosphate delta-isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in dimethylallyl diphosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in ergosterol biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in farnesyl diphosphate biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in isopentenyl diphosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol HDA PubMed 
located_in nucleus HDA PubMed 
is_active_in vacuole NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
isopentenyl-diphosphate delta-isomerase IDI1
NP_015208.1
  • Isopentenyl diphosphate:dimethylallyl diphosphate isomerase; catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability; isopentenyl diphosphate:dimethylallyl diphosphate isomerase is also known as IPP isomerase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    327864..328730 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183931.1NP_015208.1  TPA: isopentenyl-diphosphate delta-isomerase IDI1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015208.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3Q1, P15496
    UniProtKB/TrEMBL
    A0A6A5Q2P4, A6ZWD5, B5VT49, C7GJ70, C8ZIR3, G2WP65, N1NW25
    Conserved Domains (1) summary
    COG1443
    Location:69281
    Idi; Isopentenyldiphosphate isomerase [Lipid transport and metabolism]