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CSM4 Csm4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855901, updated on 18-Jan-2023

Summary

Gene symbol
CSM4
Gene description
Csm4p
Primary source
SGD:S000006121
Locus tag
YPL200W
See related
AllianceGenome:SGD:S000006121
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables cytoskeleton-nuclear membrane anchor activity. Involved in homologous chromosome pairing at meiosis; meiotic telomere clustering; and regulation of reciprocal meiotic recombination. Located in chromosome, telomeric region; endoplasmic reticulum membrane; and nuclear outer membrane. Part of meiotic nuclear membrane microtubule tethering complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See CSM4 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (171484..171954)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Aft2p Neighboring gene Yig1p Neighboring gene uncharacterized protein Neighboring gene ribosomal 60S subunit protein L7B Neighboring gene ncRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables cytoskeleton-nuclear membrane anchor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
part_of meiotic nuclear membrane microtubule tethering complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Csm4p
NP_015124.1
  • Protein required for accurate chromosome segregation during meiosis; involved in meiotic telomere clustering (bouquet formation) and telomere-led rapid prophase movements; functions with meiosis-specific telomere-binding protein Ndj1p; CSM4 has a paralog, MPS2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    171484..171954
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184014.1NP_015124.1  TPA: Csm4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015124.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3G9, Q08955
    UniProtKB/TrEMBL
    A0A8H4F855, B3LKM9, N1NW99