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RVB2 RuvB family ATP-dependent DNA helicase reptin [ Saccharomyces cerevisiae S288C ]

Gene ID: 855841, updated on 5-Sep-2021

Summary

Gene symbol
RVB2
Gene description
RuvB family ATP-dependent DNA helicase reptin
Primary source
SGD:S000006156
Locus tag
YPL235W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TIH2; TIP48; TIP49B
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Genomic context

See RVB2 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (103232..104647)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene translation initiation factor eIF2 subunit beta Neighboring gene putative serine/threonine protein kinase ENV7 Neighboring gene H(+)-transporting V0 sector ATPase subunit c' Neighboring gene MIND complex subunit NSL1

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RVB2 gene: The RVB2 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 3'-5' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 5'-3' DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA helicase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in box C/D snoRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in box C/D snoRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
 
involved_in chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in chromatin remodeling IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in histone acetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in histone exchange IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of ASTRA complex HDA PubMed 
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Ino80 complex IEA
Inferred from Electronic Annotation
more info
 
part_of Ino80 complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of NuA4 histone acetyltransferase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of NuA4 histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 
part_of R2TP complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of R2TP complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of R2TP complex IEA
Inferred from Electronic Annotation
more info
 
part_of R2TP complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of Swr1 complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RuvB family ATP-dependent DNA helicase reptin
NP_015089.1
  • ATP-dependent DNA helicase, also known as reptin; member of the AAA+ and RuvB protein families, similar to Rvb1p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    103232..104647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184049.1NP_015089.1  TPA: RuvB family ATP-dependent DNA helicase reptin [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015089.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q12464
    Conserved Domains (1) summary
    COG1224
    Location:4448
    TIP49; DNA helicase TIP49, TBP-interacting protein [Transcription]
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