Format

Send to:

Choose Destination

HSP82 Hsp90 family chaperone HSP82 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855836, updated on 5-Sep-2021

Summary

Gene symbol
HSP82
Gene description
Hsp90 family chaperone HSP82
Primary source
SGD:S000006161
Locus tag
YPL240C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HSP90
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See HSP82 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (96496..98625, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Iqg1p Neighboring gene GTPase-activating protein CIN2 Neighboring gene Yar1p Neighboring gene translation initiation factor eIF2 subunit beta

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the HSP82 gene: The HSP82 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in 'de novo' protein folding IDA
Inferred from Direct Assay
more info
PubMed 
involved_in 'de novo' protein folding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in box C/D snoRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of telomere maintenance via telomerase IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of telomere maintenance via telomerase IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in proteasome assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in proteasome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
 
involved_in protein maturation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein refolding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein stabilization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein targeting to mitochondrion IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in response to osmotic stress IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in perinuclear region of cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of protein-containing complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
Hsp90 family chaperone HSP82
NP_015084.1
  • Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; promotes solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication; human homolog, HSP90AB1, complements null mutant

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    96496..98625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184054.1NP_015084.1  TPA: Hsp90 family chaperone HSP82 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015084.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P02829
    Conserved Domains (1) summary
    PTZ00272
    Location:3709
    PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
Support Center