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PUB1 Pub1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855716, updated on 18-Nov-2018

Summary

Gene symbol
PUB1
Gene description
Pub1p
Primary source
SGD:S000004961
Locus tag
YNL016W
Gene type
protein coding
RNA name
Pub1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RNP1

Genomic context

See PUB1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (602907..604268)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene tRNA Neighboring gene Pbi2p Neighboring gene translation elongation factor EF-3

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the PUB1 gene: The PUB1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, S.cerevisiae, K.lactis, E.gossypii, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
mRNA binding HDA PubMed 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
mRNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
poly(U) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IDA
Inferred from Direct Assay
more info
PubMed 
regulation of mRNA stability IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of mRNA stability IMP
Inferred from Mutant Phenotype
more info
PubMed 
stress granule assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
stress granule assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
P-body IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Pub1p
NP_014382.1
  • Poly (A)+ RNA-binding protein; abundant mRNP-component protein that binds mRNA and is required for stability of many mRNAs; component of glucose deprivation induced stress granules, involved in P-body-dependent granule assembly; implicated in regulation of translation; carries Q/N-rich domain at C- terminus, identified as candidate prion; human homolog Tia1 is critical for normal synaptic plasticity; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    602907..604268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182855.1NP_014382.1  TPA: Pub1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014382.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32588
    Conserved Domains (4) summary
    cd12614
    Location:77150
    RRM1_PUB1; RNA recognition motif 1 in yeast nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 and similar proteins
    cd12619
    Location:163237
    RRM2_PUB1; RNA recognition motif 2 in yeast nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 and similar proteins
    cd12622
    Location:341414
    RRM3_PUB1; RNA recognition motif 3 in yeast nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1 and similar proteins
    TIGR01661
    Location:77407
    ELAV_HUD_SF; ELAV/HuD family splicing factor
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