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NST1 Nst1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855633, updated on 2-Nov-2024

Summary

Official Symbol
NST1
Official Full Name
Nst1p
Primary source
SGD:S000005035
Locus tag
YNL091W
See related
AllianceGenome:SGD:S000005035; FungiDB:YNL091W; VEuPathDB:YNL091W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in response to salt stress. Acts upstream of or within negative regulation of translation. Located in P-body. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See NST1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (452408..456130)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Rab family GTPase YPT53 Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene Rho family GTPase RHO2 Neighboring gene DNA topoisomerase 2

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Nst1p
NP_014308.1
  • Translational inhibitor and suppressor of proteasome-assembly defects; P-body component that inhibits translation, rescues proteasome base assembly defects and aggregation of regulatory particle subunits during stress when overexpressed; proposed to function to bridge the HOG and pheromone pathways with the cell wall integrity pathway in response to heat stress; interacts physically and genetically with splicing factor MSL1; large, highly-charge protein containing many disordered regions

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    452408..456130
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182929.1NP_014308.1  TPA: Nst1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014308.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W189, P53935, Q45TZ3
    UniProtKB/TrEMBL
    B3LNU9
    Conserved Domains (2) summary
    pfam13945
    Location:103159
    NST1; Salt tolerance down-regulator
    pfam15346
    Location:694727
    ARGLU; Arginine and glutamate-rich 1