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S-adenosylmethionine-dependent methyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 855632, updated on 10-Feb-2026
Official Full Name
S-adenosylmethionine-dependent methyltransferase
Primary source
SGD:S000005036
Locus tag
YNL092W
See related
AllianceGenome:SGD:S000005036; FungiDB:YNL092W; VEuPathDB:YNL092W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables S-adenosylmethionine-dependent methyltransferase activity. Involved in protein methylation. Orthologous to human CARNMT1 (carnosine N-methyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (450871..452073)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene phosphatidate phosphatase APP1 Neighboring gene Rab family GTPase YPT53 Neighboring gene Nst1p Neighboring gene Rho family GTPase RHO2

Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Substrate Recognition Mechanism of the Putative Yeast Carnosine N-methyltransferase. Liu X, et al. ACS Chem Biol, 2017 Aug 18. PMID 28654751
  2. UPF0586 Protein C9orf41 Homolog Is Anserine-producing Methyltransferase. Drozak J, et al. J Biol Chem, 2015 Jul 10. PMID 26001783, Free PMC Article
  3. Probabilistic approach to predicting substrate specificity of methyltransferases. Szczepińska T, et al. PLoS Comput Biol, 2014 Mar. PMID 24651469, Free PMC Article
  4. Yeast Nst1 is a novel component of P-bodies and is a specific suppressor of proteasome base assembly defects. Cheng CL, et al. Mol Biol Cell, 2021 Oct 1. PMID 34347506, Free PMC Article
  5. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables S-adenosylmethionine-dependent methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables S-adenosylmethionine-dependent methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables S-adenosylmethionine-dependent methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables carnosine N-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables carnosine N-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carnosine metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein methylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
Preferred Names
S-adenosylmethionine-dependent methyltransferase
NP_014307.1
  • S-adenosylmethionine-dependent protein methyltransferase; capable of automethylation; member of the seven beta-strand family; YNL092W is not an essential gene

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    450871..452073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182930.1 → NP_014307.1  S-adenosylmethionine-dependent methyltransferase

    See identical proteins and their annotated locations for NP_014307.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W188, P53934, Q45TZ4
    UniProtKB/TrEMBL
    A0A0G3F7A4, B3LNV0, B5VQV1, C8ZGD9, N1P4F0
    Conserved Domains (1) summary
    pfam07942
    Location:88 → 396
    N2227; N2227-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53934.1

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