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RPC19 DNA-directed RNA polymerase core subunit RPC19 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855609, updated on 6-Oct-2020

Summary

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Gene symbol
RPC19
Gene description
DNA-directed RNA polymerase core subunit RPC19
Primary source
SGD:S000005057
Locus tag
YNL113W
Gene type
protein coding
RNA name
DNA-directed RNA polymerase core subunit RPC19
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

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See RPC19 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (412771..413199)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating protein DMA2 Neighboring gene hypothetical protein Neighboring gene DEAD-box ATP-dependent RNA helicase DBP2 Neighboring gene Cyb5p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Association of the GTP-binding protein Gtr1p with Rpc19p, a shared subunit of RNA polymerase I and III in yeast Saccharomyces cerevisiae. Todaka Y, et al. Genetics, 2005 Aug. PMID 15937128, Free PMC Article
  2. Interactions between three common subunits of yeast RNA polymerases I and III. Lalo D, et al. Proc Natl Acad Sci U S A, 1993 Jun 15. PMID 8516295, Free PMC Article
  3. The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription. Torreira E, et al. Elife, 2017 Mar 6. PMID 28262097, Free PMC Article
  4. Yeast Bud27 modulates the biogenesis of Rpc128 and Rpc160 subunits and the assembly of RNA polymerase III. Vernekar DV, et al. Biochim Biophys Acta, 2015 Nov. PMID 26423792
  5. Cohesion promotes nucleolar structure and function. Harris B, et al. Mol Biol Cell, 2014 Feb. PMID 24307683, Free PMC Article

See all (63) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

  • Homologs of the RPC19 gene: The RPC19 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
  
contributes_to DNA-directed 5'-3' RNA polymerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to RNA polymerase I activity IDA
Inferred from Direct Assay
more info
 PubMed 
contributes_to RNA polymerase III activity IDA
Inferred from Direct Assay
more info
 PubMed 
protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
tRNA transcription by RNA polymerase III IDA
Inferred from Direct Assay
more info
 PubMed 
transcription by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
RNA polymerase III complex IDA
Inferred from Direct Assay
more info
 PubMed 
nucleolus IEA
Inferred from Electronic Annotation
more info
  
nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase core subunit RPC19
NP_014286.1
  • RNA polymerase subunit AC19; common to RNA polymerases I and III

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    412771..413199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182951.1 → NP_014286.1  TPA: DNA-directed RNA polymerase core subunit RPC19 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014286.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P28000
    Conserved Domains (1) summary
    cd07029
    Location:52 → 135
    RNAP_I_III_AC19; AC19 subunit of Eukaryotic RNA polymerase (RNAP) I and RNAP III
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
5LMX_K.1
5M3F_K.1
5M3M_K.1
5M5W_K.1
5N60_K.1
5N61_K.1
5OA1_K.1
5W5Y_K.1
5W64_K.1
5W65_K.1
5W66_K.1
6CNB_K.1
6CNC_K.1
6CND_K.1
6CNF_K.1
6EU0_K.1
6EU1_K.1
6EU2_K.1
6EU3_K.1
6F40_K.1
6F41_K.1
6F42_K.1
6F44_K.1
6H67_K.1
6H68_K.1
6HKO_K.1
6HLQ_K.1
6HLR_K.1
6HLS_K.1
6TUT_K.1
P28000.1

Gene LinkOut

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