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NAF1 RNA-binding snoRNP assembly protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855599, updated on 18-Jan-2023

Summary

Gene symbol
NAF1
Gene description
RNA-binding snoRNP assembly protein
Primary source
SGD:S000005068
Locus tag
YNL124W
See related
AllianceGenome:SGD:S000005068
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA binding activity. Involved in box H/ACA snoRNP assembly. Located in nucleoplasm. Orthologous to human NAF1 (nuclear assembly factor 1 ribonucleoprotein). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See NAF1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (392892..394370)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Spc98p Neighboring gene Esbp6p Neighboring gene Nma111p Neighboring gene Mrp35p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables RNA binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in box H/ACA snoRNP assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in box H/ACA snoRNP assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in box H/ACA snoRNP assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in box H/ACA snoRNP assembly IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosome biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of sno(s)RNA-containing ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of sno(s)RNA-containing ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
RNA-binding snoRNP assembly protein
NP_014275.3
  • RNA-binding protein required for the assembly of box H/ACA snoRNPs; thus required for pre-rRNA processing; forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    392892..394370
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182962.3NP_014275.3  TPA: RNA-binding snoRNP assembly protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014275.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W159, P53919
    UniProtKB/TrEMBL
    A0A8H4BVP3, N1NWI9
    Conserved Domains (2) summary
    PRK10263
    Location:343448
    PRK10263; DNA translocase FtsK; Provisional
    pfam04410
    Location:119263
    Gar1; Gar1/Naf1 RNA binding region