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SSB2 Hsp70 family ATPase SSB2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855512, updated on 4-Feb-2024

Summary

Gene symbol
SSB2
Gene description
Hsp70 family ATPase SSB2
Primary source
SGD:S000005153
Locus tag
YNL209W
See related
AllianceGenome:SGD:S000005153
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YG103
Summary
Enables ATP hydrolysis activity and unfolded protein binding activity. Involved in several processes, including 'de novo' cotranslational protein folding; ribosome biogenesis; and translation. Located in cytoplasmic stress granule and plasma membrane. Part of polysome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See SSB2 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (252059..253900)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Mrx7p Neighboring gene Mer1p Neighboring gene uncharacterized protein Neighboring gene protein kinase RIO2

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ATP hydrolysis activity IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
 
enables heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein folding chaperone IBA
Inferred from Biological aspect of Ancestor
more info
 
enables unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in 'de novo' cotranslational protein folding IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cellular response to glucose starvation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cytoplasmic translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cytoplasmic translation IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in rRNA processing IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in regulation of translational fidelity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ribosomal subunit export from nucleus IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translational frameshifting IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic stress granule HDA PubMed 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Hsp70 family ATPase SSB2
NP_014190.1
  • Cytoplasmic ATPase that is a ribosome-associated molecular chaperone; functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; SSB2 has a paralog, SSB1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    252059..253900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183047.1NP_014190.1  TPA: Hsp70 family ATPase SSB2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014190.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0Y1, P40150
    UniProtKB/TrEMBL
    A0A8H4BVK0, A6ZRN1, B3LP53, G2WLQ4
    Conserved Domains (1) summary
    PTZ00009
    Location:6575
    PTZ00009; heat shock 70 kDa protein; Provisional