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SSB2 Hsp70 family ATPase SSB2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855512, updated on 5-Aug-2018

Summary

Gene symbol
SSB2
Gene description
Hsp70 family ATPase SSB2
Primary source
SGD:S000005153
Locus tag
YNL209W
Gene type
protein coding
RNA name
Hsp70 family ATPase SSB2
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YG103

Genomic context

See SSB2 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (252059..253900)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Mrx7p Neighboring gene Mer1p Neighboring gene hypothetical protein Neighboring gene protein kinase RIO2

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Longevity regulating pathway - multiple species, organism-specific biosystem (from KEGG)
    Longevity regulating pathway - multiple species, organism-specific biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Longevity regulating pathway - multiple species, conserved biosystem (from KEGG)
    Longevity regulating pathway - multiple species, conserved biosystemAging is a complex process of accumulation of molecular, cellular, and organ damage, leading to loss of function and increased vulnerability to disease and death. Despite the complexity of aging, rec...
  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Spliceosome, organism-specific biosystem (from KEGG)
    Spliceosome, organism-specific biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...
  • Spliceosome, conserved biosystem (from KEGG)
    Spliceosome, conserved biosystemAfter transcription, eukaryotic mRNA precursors contain protein-coding exons and noncoding introns. In the following splicing, introns are excised and exons are joined by a macromolecular complex, th...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
ATPase activity, coupled IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heat shock protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
misfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding involved in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unfolded protein binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
'de novo' cotranslational protein folding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
'de novo' cotranslational protein folding IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to glucose starvation IGI
Inferred from Genetic Interaction
more info
PubMed 
cellular response to heat IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chaperone cofactor-dependent protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic translation IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytoplasmic translation IPI
Inferred from Physical Interaction
more info
PubMed 
protein refolding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA processing IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of translational fidelity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of translational fidelity IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to unfolded protein IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosomal subunit export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosomal subunit export from nucleus IGI
Inferred from Genetic Interaction
more info
PubMed 
translation IEA
Inferred from Electronic Annotation
more info
 
translational frameshifting IMP
Inferred from Mutant Phenotype
more info
PubMed 
translational termination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane HDA PubMed 
polysome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
polysome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Hsp70 family ATPase SSB2
NP_014190.1
  • Cytoplasmic ATPase that is a ribosome-associated molecular chaperone; functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; SSB2 has a paralog, SSB1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    252059..253900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183047.1NP_014190.1  TPA: Hsp70 family ATPase SSB2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014190.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40150
    Conserved Domains (2) summary
    cd10233
    Location:9384
    HSPA1-2_6-8-like_NBD; Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins
    pfam00012
    Location:9608
    HSP70; Hsp70 protein
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