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NRD1 Nrd1 complex RNA-binding subunit [ Saccharomyces cerevisiae S288C ]

Gene ID: 855470, updated on 9-Dec-2024

Summary

Official Symbol
NRD1
Official Full Name
Nrd1 complex RNA-binding subunit
Primary source
SGD:S000005195
Locus tag
YNL251C
See related
AllianceGenome:SGD:S000005195; FungiDB:YNL251C; VEuPathDB:YNL251C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein domain specific binding activity and transcription regulatory region RNA binding activity. Involved in RNA metabolic process. Part of Nrd1 complex. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

See NRD1 in Genome Data Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (172588..174315, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Tex1p Neighboring gene mitochondrial 54S ribosomal protein YmL17/YmL30 Neighboring gene MRX complex DNA-binding subunit Neighboring gene Mpa43p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding HDA PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription regulatory region RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of Nrd1 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Nrd1 complex IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Nrd1 complex RNA-binding subunit
NP_014148.1
  • RNA-binding subunit of Nrd1 complex; complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; interacts with CTD of RNA pol II large subunit Rpo21p at phosphorylated Ser5 to direct transcription termination of non-polyadenylated transcripts; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; role in regulation of mitochondrial abundance and cell size

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    172588..174315 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183089.1NP_014148.1  TPA: Nrd1 complex RNA-binding subunit [Saccharomyces cerevisiae S288C]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0U2, P53617
    UniProtKB/TrEMBL
    A6ZRJ2, B3LP95, C7GPB0, C8ZFY6, G2WLL5, N1NZY7
    Conserved Domains (2) summary
    cd16984
    Location:8149
    CID_Nrd1_like; CID (CTD-Interacting Domain) of Nrd1 and similar proteins
    cd12331
    Location:336412
    RRM_NRD1_SEB1_like; RNA recognition motif (RRM) found in Saccharomyces cerevisiae protein Nrd1, Schizosaccharomyces pombe Rpb7-binding protein seb1 and similar proteins