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FIG4 phosphatidylinositol-3,5-bisphosphate 5-phosphatase [ Saccharomyces cerevisiae S288c ]

Gene ID: 855392, updated on 5-Mar-2017
Gene symbol
FIG4
Gene description
phosphatidylinositol-3,5-bisphosphate 5-phosphatase
Primary source
SGD:S000005269
Locus tag
YNL325C
Gene type
protein coding
RNA name
phosphatidylinositol-3,5-bisphosphate 5-phosphatase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See FIG4 in Map Viewer
Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (28739..31378, complement)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene Egt2p Neighboring gene palmitoyltransferase PFA3 Neighboring gene Lem3p Neighboring gene Kre1p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
phosphoric ester hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
phosphatidylinositol dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
phosphatidylinositol dephosphorylation IGI
Inferred from Genetic Interaction
more info
PubMed 
phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
PAS complex IDA
Inferred from Direct Assay
more info
PubMed 
PAS complex IPI
Inferred from Physical Interaction
more info
PubMed 
extrinsic component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear periphery IDA
Inferred from Direct Assay
more info
PubMed 
vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
vacuole IEA
Inferred from Electronic Annotation
more info
 
Names
phosphatidylinositol-3,5-bisphosphate 5-phosphatase
NP_014074.1
  • Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase; required for efficient mating and response to osmotic shock; physically associates with and regulated by Vac14p; contains a SAC1-like domain; homologous to human FIG4, which is associated with CMT4J, a form of Charcot-Marie-Tooth disorder

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    28739..31378 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183163.1NP_014074.1  TPA: phosphatidylinositol-3,5-bisphosphate 5-phosphatase [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_014074.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P42837
    Conserved Domains (2) summary
    COG5329
    Location:31653
    COG5329; Phosphoinositide polyphosphatase (Sac family) [Signal transduction mechanisms]
    pfam02383
    Location:104423
    Syja_N; SacI homology domain
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