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SCS7 fatty acid alpha-hydroxylase [ Saccharomyces cerevisiae S288c ]

Gene ID: 855315, updated on 29-Oct-2016
Gene symbol
SCS7
Gene description
fatty acid alpha-hydroxylase
Primary source
SGD:S000004885
Locus tag
YMR272C
Gene type
protein coding
RNA name
fatty acid alpha-hydroxylase
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
FAH1
See SCS7 in Map Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (809623..810777, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene orotate phosphoribosyltransferase URA10 Neighboring gene tRNA Neighboring gene hypothetical protein Neighboring gene Zds1p

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
fatty acid alpha-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 
fatty acid alpha-hydroxylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
heme binding IEA
Inferred from Electronic Annotation
more info
 
iron ion binding IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
inositolphosphoceramide metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
inositolphosphoceramide metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Names
fatty acid alpha-hydroxylase
NP_013999.1
  • Sphingolipid alpha-hydroxylase; functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    809623..810777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182779.1NP_013999.1  TPA: fatty acid alpha-hydroxylase [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_013999.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q03529
    Conserved Domains (4) summary
    COG3000
    Location:232377
    ERG3; Sterol desaturase/sphingolipid hydroxylase, fatty acid hydroxylase superfamily [Lipid transport and metabolism]
    COG5274
    Location:31224
    CYB5; Cytochrome b involved in lipid metabolism [Energy production and conversion, Lipid transport and metabolism]
    pfam00173
    Location:1189
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    cl01132
    Location:149380
    FA_hydroxylase; Fatty acid hydroxylase superfamily
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