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DML1 Dml1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855251, updated on 3-Jun-2026
Official Symbol
DML1
Official Full Name
Dml1p
Primary source
SGD:S000004824
Locus tag
YMR211W
See related
AllianceGenome:SGD:S000004824; FungiDB:YMR211W; VEuPathDB:YMR211W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in mitochondrial genome maintenance and plasmid maintenance. Located in mitochondrion. Orthologous to human MSTO1 (misato mitochondrial distribution and morphology regulator 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See DML1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (689083..690510)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene putative carboxylic ester hydrolase Neighboring gene Efr3p Neighboring gene Cef1p

Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster. Gurvitz A, et al. FEMS Yeast Res, 2002 May. PMID 12702300
  2. Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae. Aye M, et al. Genetics, 2004 Nov. PMID 15579677, Free PMC Article
  3. Btn3 regulates the endosomal sorting function of the yeast Ent3 epsin, an adaptor for SNARE proteins. Morvan J, et al. J Cell Sci, 2015 Feb 15. PMID 25512335
  4. Dosage suppression genetic interaction networks enhance functional wiring diagrams of the cell. Magtanong L, et al. Nat Biotechnol, 2011 May 15. PMID 21572441, Free PMC Article
  5. Heterozygous screen in Saccharomyces cerevisiae identifies dosage-sensitive genes that affect chromosome stability. Strome ED, et al. Genetics, 2008 Mar. PMID 18245329, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrion organization IEA
Inferred from Electronic Annotation
more info
  
involved_in plasmid maintenance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm EXP
Inferred from Experiment
more info
 PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion EXP
Inferred from Experiment
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Dml1p
NP_013938.1
  • Essential protein involved in mtDNA inheritance; may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    689083..690510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182718.1 → NP_013938.1  Dml1p

    See identical proteins and their annotated locations for NP_013938.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W036, Q03652
    UniProtKB/TrEMBL
    A6ZMS3, B3LM99, C7GRE0, C8ZF75
    Conserved Domains (1) summary
    cl10017
    Location:2 → 290
    Tubulin_FtsZ_Cetz-like; Tubulin protein family of FtsZ and CetZ-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03652.1

Gene LinkOut

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