MTG1 putative GTPase MTG1 [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: MTG1
Official Full Name: putative GTPase MTG1
Primary source: SGD:S000004703
Locus tag: YMR097C
See related: AllianceGenome:SGD:S000004703; FungiDB:YMR097C; VEuPathDB:YMR097C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Predicted to enable GTPase activity. Involved in mitochondrial large ribosomal subunit assembly. Located in mitochondrial inner membrane. Orthologous to human MTG1 (mitochondrial ribosome associated GTPase 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs: all
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Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	ISA Inferred from Sequence Alignment more info	PubMed

Process	Evidence Code	Pubs
involved_in mitochondrial large ribosomal subunit assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial large ribosomal subunit assembly	IGI Inferred from Genetic Interaction more info	PubMed
involved_in mitochondrial large ribosomal subunit assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of mitochondrial translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	EXP Inferred from Experiment more info	PubMed
located_in mitochondrial inner membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	HDA more info	PubMed

NP_013815.1

Putative GTPase peripheral to the mitochondrial inner membrane; essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals

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The following sections contain reference sequences that belong to a specific genome build. Explain