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SNZ1 pyridoxine biosynthesis protein SNZ1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 855121, updated on 23-Apr-2026
Official Symbol
SNZ1
Official Full Name
pyridoxine biosynthesis protein SNZ1
Primary source
SGD:S000004702
Locus tag
YMR096W
See related
AllianceGenome:SGD:S000004702; FungiDB:YMR096W; VEuPathDB:YMR096W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity. Involved in pyridoxine biosynthetic process. Part of glutaminase complex. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See SNZ1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (458408..459301)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Ctf13p Neighboring gene putative pyridoxal 5'-phosphate synthase Neighboring gene putative GTPase MTG1 Neighboring gene Atp25p

Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Protein synthesis in long-term stationary-phase cultures of Saccharomyces cerevisiae. Fuge EK, et al. J Bacteriol, 1994 Sep. PMID 8083172, Free PMC Article
  2. GintPDX1 encodes a protein involved in vitamin B6 biosynthesis that is up-regulated by oxidative stress in the arbuscular mycorrhizal fungus Glomus intraradices. Benabdellah K, et al. New Phytol, 2009 Nov. PMID 19674326
  3. Structural insights into the catalytic mechanism of the yeast pyridoxal 5-phosphate synthase Snz1. Zhang X, et al. Biochem J, 2010 Dec 15. PMID 20919991
  4. X-ray crystal structure of Saccharomyces cerevisiae Pdx1 provides insights into the oligomeric nature of PLP synthases. Neuwirth M, et al. FEBS Lett, 2009 Jul 7. PMID 19523954
  5. Characterization of the products of the genes SNO1 and SNZ1 involved in pyridoxine synthesis in Saccharomyces cerevisiae. Dong YX, et al. Eur J Biochem, 2004 Feb. PMID 14764090

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables amine-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-glutamine catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pyridoxal 5'-phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyridoxal 5'-phosphate biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pyridoxal 5'-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pyridoxine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in pyridoxine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in pyridoxine biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in pyridoxine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vitamin B6 biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in vitamin B6 biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of glutaminase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
pyridoxine biosynthesis protein SNZ1
NP_013814.1
  • Subunit of a two-component pyridoxal-5'-phosphate synthase; involved in pyridoxine (vitamin B6) biosynthesis from glyceraldehyde-3-phosphate, ribose-5-phosphate and ammonia liberated from glutamine by glutaminase; forms a complex with Sno1p that functions as an active glutaminase; member of a stationary phase-induced gene family where transcriptional induction occurs during the postdiauxic phase; co-regulated with SNO1; paralog of SNZ2 and SNZ3

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    458408..459301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182596.1 → NP_013814.1  pyridoxine biosynthesis protein SNZ1

    See identical proteins and their annotated locations for NP_013814.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZR9, Q03148
    UniProtKB/TrEMBL
    A6ZMF3, B3LLY7, B5VPM3, C7GL30, C8ZEU8, G2WKE4, N1P0A8
    Conserved Domains (1) summary
    TIGR00343
    Location:8 → 297
    TIGR00343; pyridoxal 5'-phosphate synthase, synthase subunit Pdx1
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03148.1

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