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MIX17 Mix17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855014, updated on 29-Jun-2024

Summary

Gene symbol
MIX17
Gene description
Mix17p
Primary source
FungiDB:YMR002W
Locus tag
YMR002W
See related
SGD:S000004604; AllianceGenome:SGD:S000004604; VEuPathDB:YMR002W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MIC17
Summary
Involved in aerobic respiration. Located in mitochondrial intermembrane space. Human ortholog(s) of this gene implicated in Parkinson's disease 22 and frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Orthologous to several human genes including CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See MIX17 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (272193..272663)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene polo kinase CDC5 Neighboring gene uncharacterized protein Neighboring gene Aim34p Neighboring gene Mvp1p

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in aerobic respiration IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrion organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in mitochondrial intermembrane space IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial intermembrane space IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Mix17p
NP_013715.1
  • Mitochondrial intermembrane space protein; required for normal oxygen consumption; contains twin cysteine-x9-cysteine motifs; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    272193..272663
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182498.1NP_013715.1  TPA: Mix17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013715.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZH7, Q03667
    UniProtKB/TrEMBL
    A0A6A5PRA8, A6ZM64, C8ZEK8, N1P5B3
    Conserved Domains (1) summary
    pfam06747
    Location:118152
    CHCH; CHCH domain