U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ERV25 Erv25p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854997, updated on 23-Jul-2026
Official Symbol
ERV25
Official Full Name
Erv25p
Primary source
SGD:S000004473
Locus tag
YML012W
See related
AllianceGenome:SGD:S000004473; FungiDB:YML012W; VEuPathDB:YML012W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in COPII-coated ER to Golgi transport vesicle. Orthologous to human TMED10 (transmembrane p24 trafficking protein 10). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See ERV25 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (246116..246751)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene tRNA (carboxymethyluridine(34)-5-O)-methyltransferase Neighboring gene Ubx2p Neighboring gene Rad33p Neighboring gene transcription elongation factor SPT5

Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Erv25p, a component of COPII-coated vesicles, forms a complex with Emp24p that is required for efficient endoplasmic reticulum to Golgi transport. Belden WJ, et al. J Biol Chem, 1996 Oct 25. PMID 8900179
  2. Identification of a lumenal sequence specifying the assembly of Emp24p into p24 complexes in the yeast secretory pathway. Ciufo LF, et al. J Biol Chem, 2000 Mar 24. PMID 10722670
  3. The Emp24 complex recruits a specific cargo molecule into endoplasmic reticulum-derived vesicles. Muñiz M, et al. J Cell Biol, 2000 Mar 6. PMID 10704443, Free PMC Article
  4. The Erv41p-Erv46p complex: multiple export signals are required in trans for COPII-dependent transport from the ER. Otte S, et al. EMBO J, 2002 Nov 15. PMID 12426381, Free PMC Article
  5. Deletion of yeast p24 genes activates the unfolded protein response. Belden WJ, et al. Mol Biol Cell, 2001 Apr. PMID 11294899, Free PMC Article

See all (75) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in vesicle budding from membrane NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in COPII-coated ER to Golgi transport vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in COPII-coated ER to Golgi transport vesicle IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi-associated vesicle NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type vacuole HDA PubMed 
Preferred Names
Erv25p
NP_013701.1
  • Member of the p24 family involved in ER to Golgi transport; role in misfolded protein quality control; forms a heterotrimeric complex with Erp1, Erp2p, and Emp24

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    246116..246751
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182369.1 → NP_013701.1  Erv25p

    See identical proteins and their annotated locations for NP_013701.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZG2, P54837
    UniProtKB/TrEMBL
    B3LLN9
    Conserved Domains (1) summary
    pfam01105
    Location:20 → 206
    EMP24_GP25L; emp24/gp25L/p24 family/GOLD
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P54837.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous