TAF11 TATA-binding protein-associated factor TAF11 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: TAF11
Official Full Name: TATA-binding protein-associated factor TAF11
Primary source: SGD:S000004477
Locus tag: YML015C
See related: AllianceGenome:SGD:S000004477; FungiDB:YML015C; VEuPathDB:YML015C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: TAF40
Summary: Enables chromatin binding activity. Involved in RNA polymerase II preinitiation complex assembly. Part of transcription factor TFIID complex. Orthologous to several human genes including TAF11 (TATA-box binding protein associated factor 11). [provided by Alliance of Genome Resources, Mar 2025]
Orthologs: all
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Genomic context

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See TAF11 in Genome Data Viewer

Location:: chromosome: XIII

Exon count:: 1

Sequence:: Chromosome: XIII; NC_001145.3 (241989..243029, complement)

Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interaction between TAF11 and TFIIA involves two distinct regions of TAF11
Title: Mapping and functional characterization of the TAF11 interaction with TFIIA.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	IDA Inferred from Direct Assay more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within RNA polymerase II preinitiation complex assembly	IEA Inferred from Electronic Annotation more info
involved_in RNA polymerase II preinitiation complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in transcription by RNA polymerase II	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIID complex	IDA Inferred from Direct Assay more info	PubMed
part_of transcription factor TFIID complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: TATA-binding protein-associated factor TAF11

NP_013697.1

TFIID subunit (40 kDa); involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001145.3 Reference assembly

Range

241989..243029 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001182373.1 → NP_013697.1 TPA: TATA-binding protein-associated factor TAF11 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_013697.1

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VZF9, Q04226

UniProtKB/TrEMBL

A6ZM47, B3LLN7, B5VPB0, C7GLD3, G2WK37, N1P035

Conserved Domains (1) summary

COG5251
Location:31 → 230

TAF40; Transcription initiation factor TFIID, subunit TAF11 [Transcription]