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PPZ1 salt homeostasis regulator [ Saccharomyces cerevisiae S288C ]

Gene ID: 854992, updated on 14-Nov-2024

Summary

Official Symbol
PPZ1
Official Full Name
salt homeostasis regulator
Primary source
SGD:S000004478
Locus tag
YML016C
See related
AllianceGenome:SGD:S000004478; FungiDB:YML016C; VEuPathDB:YML016C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein serine/threonine phosphatase activity. Involved in intracellular sodium ion homeostasis and protein localization. Located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See PPZ1 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (239458..241536, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Psp2p Neighboring gene TATA-binding protein-associated factor TAF11 Neighboring gene tRNA (carboxymethyluridine(34)-5-O)-methyltransferase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables MAP kinase serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables calmodulin-dependent protein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables histone H2AXS140 phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 
involved_in intracellular sodium ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
salt homeostasis regulator
NP_013696.1
  • Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    239458..241536 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182374.1NP_013696.1  TPA: salt homeostasis regulator [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013696.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZF8, P26570, Q00979
    UniProtKB/TrEMBL
    A6ZM46, B3LLN6, B5VPA9, C7GLD4, C8ZEI8, G2WK36, N1NYJ4
    Conserved Domains (1) summary
    cd07414
    Location:362653
    MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain