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RAD52 recombinase RAD52 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854976, updated on 19-Oct-2021

Summary

Gene symbol
RAD52
Gene description
recombinase RAD52
Primary source
SGD:S000004494
Locus tag
YML032C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See RAD52 in Genome Data Viewer
Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (212515..213930, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene AMP deaminase Neighboring gene Src1p Neighboring gene Ndc1p Neighboring gene Rcf1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables DNA strand exchange activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA/DNA annealing activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA amplification IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in DNA recombinase assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in DNA recombinase assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair via break-induced replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in double-strand break repair via homologous recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in double-strand break repair via single-strand annealing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in double-strand break repair via single-strand annealing IEA
Inferred from Electronic Annotation
more info
 
involved_in double-strand break repair via single-strand annealing IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in meiotic joint molecule formation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in meiotic joint molecule formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrial DNA repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of DNA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
involved_in positive regulation of DNA ligase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in postreplication repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in telomere maintenance via recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
recombinase RAD52
NP_013680.2
  • Protein involved in homologous recombination; attenuates resection of DNA double-strand break ends and stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination; phosphorylation by Cdc28p in G2/M phase promotes Rad52p ring interaction that leads to superstructure formation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    212515..213930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182390.1NP_013680.2  TPA: recombinase RAD52 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013680.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P06778
    Conserved Domains (1) summary
    cl01936
    Location:1382
    Rad52_Rad22; Rad52/22 family double-strand break repair protein
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