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Klf15 Kruppel-like factor 15 [ Rattus norvegicus (Norway rat) ]

Gene ID: 85497, updated on 26-Nov-2020

Summary

Official Symbol
Klf15provided by RGD
Official Full Name
Kruppel-like factor 15provided by RGD
Primary source
RGD:70918
See related
Ensembl:ENSRNOG00000017808
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
mouse homolog is a transcription factor that is an important regulator of the glucose transporter GLUT4 [RGD, Feb 2006]
Expression
Biased expression in Kidney (RPKM 109.6), Liver (RPKM 91.5) and 9 other tissues See more
Orthologs

Genomic context

See Klf15 in Genome Data Viewer
Location:
4q34
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (122364688..122377690)
106 current Rn_Celera (GCF_000002265.2) 4 AC_000072.1 (111889901..111902497)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (186905687..186918647)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene ZXD family zinc finger C Neighboring gene cilia and flagella associated protein 100 Neighboring gene uncharacterized LOC108350819 Neighboring gene nucleoporin 210

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC108619

Gene Ontology Provided by RGD

Process Evidence Code Pubs
cardiac muscle hypertrophy in response to stress ISO
Inferred from Sequence Orthology
more info
 
cellular glucose homeostasis ISO
Inferred from Sequence Orthology
more info
 
cellular response to peptide IEP
Inferred from Expression Pattern
more info
PubMed 
glial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
glomerular visceral epithelial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of peptidyl-lysine acetylation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of glucose import ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of Wnt signaling pathway ISO
Inferred from Sequence Orthology
more info
 
regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to insulin ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053536.2NP_445988.2  Krueppel-like factor 15

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000148
    Related
    ENSRNOP00000024011.2, ENSRNOT00000024011.5

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    122364688..122377690
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017592934.1XP_017448423.1  Krueppel-like factor 15 isoform X1

    UniProtKB/TrEMBL
    Q5FVT6
    Conserved Domains (4) summary
    sd00017
    Location:322344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:320344
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:366391
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:322401
    zf-C2H2_8; C2H2-type zinc ribbon
  2. XM_008763135.2XP_008761357.1  Krueppel-like factor 15 isoform X1

    See identical proteins and their annotated locations for XP_008761357.1

    UniProtKB/TrEMBL
    Q5FVT6
    Conserved Domains (4) summary
    sd00017
    Location:322344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:320344
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:366391
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:322401
    zf-C2H2_8; C2H2-type zinc ribbon
  3. XM_006236882.3XP_006236944.1  Krueppel-like factor 15 isoform X1

    See identical proteins and their annotated locations for XP_006236944.1

    UniProtKB/TrEMBL
    Q5FVT6
    Conserved Domains (4) summary
    sd00017
    Location:322344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:320344
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:366391
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:322401
    zf-C2H2_8; C2H2-type zinc ribbon
  4. XM_008763136.1XP_008761358.1  Krueppel-like factor 15 isoform X1

    See identical proteins and their annotated locations for XP_008761358.1

    UniProtKB/TrEMBL
    Q5FVT6
    Conserved Domains (4) summary
    sd00017
    Location:322344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:320344
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:366391
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:322401
    zf-C2H2_8; C2H2-type zinc ribbon
  5. XM_006236884.3XP_006236946.1  Krueppel-like factor 15 isoform X1

    See identical proteins and their annotated locations for XP_006236946.1

    UniProtKB/TrEMBL
    Q5FVT6
    Conserved Domains (4) summary
    sd00017
    Location:322344
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:320344
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:366391
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:322401
    zf-C2H2_8; C2H2-type zinc ribbon

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    111889901..111902497
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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