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VPS71 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854966, updated on 22-Aug-2024

Summary

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Official Symbol
VPS71
Primary source
FungiDB:YML041C
Locus tag
YML041C
See related
SGD:S000004505; AllianceGenome:SGD:S000004505; VEuPathDB:YML041C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SWC6
Summary
Enables nucleosome binding activity. Involved in histone exchange. Located in nucleus. Part of Swr1 complex. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (194913..195755, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Rrn11p Neighboring gene carnitine O-acetyltransferase CAT2 Neighboring gene tRNA-Pro Neighboring gene gag protein Neighboring gene gag-pol fusion protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Roles for H2A.Z and its acetylation in GAL1 transcription and gene induction, but not GAL1-transcriptional memory. Halley JE, et al. PLoS Biol, 2010 Jun 22. PMID 20582323, Free PMC Article
  2. The essential function of Swc4p - a protein shared by two chromatin-modifying complexes of the yeast Saccharomyces cerevisiae - resides within its N-terminal part. Miciałkiewicz A, et al. Acta Biochim Pol, 2008. PMID 18726008
  3. Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing. Emre NC, et al. Mol Cell, 2005 Feb 18. PMID 15721261
  4. Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae. Lu PY, et al. Genetics, 2014 May. PMID 24578349, Free PMC Article
  5. The roles of thiol oxidoreductases in yeast replicative aging. Hacioglu E, et al. Mech Ageing Dev, 2010 Nov-Dec. PMID 20934449, Free PMC Article

See all (103) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleosome binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein targeting to vacuole HMP PubMed 
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Vps71p
NP_013671.1
  • Nucleosome-binding component of the SWR1 complex; SWR1 exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    194913..195755 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182399.1 → NP_013671.1  TPA: Vps71p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013671.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VZD4, Q03433
    UniProtKB/TrEMBL
    A6ZM24, B3LLL4, B5VP89, C7GT68, C8ZEG6, G2WK14, N1NZ15
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03433.1

Gene LinkOut

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