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RPPH1 ribonuclease P RNA component H1 [ Homo sapiens (human) ]

Gene ID: 85495, updated on 22-Jan-2023

Summary

Official Symbol
RPPH1provided by HGNC
Official Full Name
ribonuclease P RNA component H1provided by HGNC
Primary source
HGNC:HGNC:19273
See related
Ensembl:ENSG00000277209 MIM:608513; AllianceGenome:HGNC:19273
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
H1RNA; RPPH1-1
Summary
H1RNA is the RNA component of the RNase P ribonucleoprotein, an endoribonuclease that cleaves tRNA precursor molecules to form the mature 5-prime termini of their tRNA sequences (Baer et al., 1989 [PubMed 2308839]).[supplied by OMIM, Mar 2008]
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Genomic context

See RPPH1 in Genome Data Viewer
Location:
14q11.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (20343071..20343411, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (14539966..14540306, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20811230..20811570, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene cyclin B1 interacting protein 1 Neighboring gene small nucleolar RNA, H/ACA box 79B Neighboring gene small nucleolar RNA, C/D box 126 Neighboring gene poly(ADP-ribose) polymerase 2 Neighboring gene telomerase associated protein 1

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • H1 RNA

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ribonuclease P activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA phosphodiester bond hydrolysis, endonucleolytic IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ribonuclease P complex IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002312.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    CA413366, CV309337, DW429001, X15624
    Related
    ENST00000516869.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    20343071..20343411 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791796.1 Reference GRCh38.p14 PATCHES

    Range
    545752..546092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    14539966..14540306 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)