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Abcf1 ATP binding cassette subfamily F member 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 85493, updated on 13-Aug-2019

Summary

Official Symbol
Abcf1provided by RGD
Official Full Name
ATP binding cassette subfamily F member 1provided by RGD
Primary source
RGD:620286
See related
Ensembl:ENSRNOG00000000799
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Abc50
Summary
ATP-binding cassette (ABC) protein family member that associates with eIF2 and ribosomes to facilitate mRNA translation [RGD, Feb 2006]
Expression
Biased expression in Heart (RPKM 206.0), Thymus (RPKM 159.5) and 9 other tissues See more
Orthologs

Genomic context

See Abcf1 in Genome Data Viewer
Location:
20p12
Exon count:
24
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3309914..3322828)
106 current Rn_Celera (GCF_000002265.2) 20 AC_000088.1 (228398..241279)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 20 NC_005119.3 (5407475..5420356)

Chromosome 20 - NC_005119.4Genomic Context describing neighboring genes Neighboring gene G protein nucleolar 1 Neighboring gene proline rich 3 Neighboring gene uncharacterized LOC102553244 Neighboring gene microRNA 877 Neighboring gene protein phosphatase 1, regulatory subunit 10 Neighboring gene mitochondrial ribosomal protein S18B

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding ISO
Inferred from Sequence Orthology
more info
PubMed 
ATP binding ISS
Inferred from Sequence or Structural Similarity
more info
 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
ribosome binding ISO
Inferred from Sequence Orthology
more info
PubMed 
ribosome binding ISS
Inferred from Sequence or Structural Similarity
more info
 
translation activator activity ISO
Inferred from Sequence Orthology
more info
PubMed 
translation activator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
positive regulation of translation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of translation ISS
Inferred from Sequence or Structural Similarity
more info
 
NOT ribosome biogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
NOT ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
translation NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation ISO
Inferred from Sequence Orthology
more info
PubMed 
translational initiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nuclear envelope ISO
Inferred from Sequence Orthology
more info
PubMed 
nuclear envelope ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
polysomal ribosome ISO
Inferred from Sequence Orthology
more info
PubMed 
polysomal ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 
ribosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ATP-binding cassette sub-family F member 1
Names
ATP-binding cassette 50
ATP-binding cassette, sub-family F (GCN20), member 1
ATP-binding cassette, subfamily F (GCN20), member 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001109883.2NP_001103353.1  ATP-binding cassette sub-family F member 1

    See identical proteins and their annotated locations for NP_001103353.1

    Status: VALIDATED

    Source sequence(s)
    BP495802, BX883048, CB801303, CK356298, CV114142, EV771702, EV773343
    UniProtKB/Swiss-Prot
    Q6MG08
    Related
    ENSRNOP00000001049.6, ENSRNOT00000001049.7
    Conserved Domains (2) summary
    cd03221
    Location:298519
    ABCF_EF-3; ATP-binding cassette domain of elongation factor 3, subfamily F
    COG0488
    Location:296827
    Uup; ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005119.4 Reference Rnor_6.0 Primary Assembly

    Range
    3309914..3322828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017601783.1XP_017457272.1  ATP-binding cassette sub-family F member 1 isoform X1

Alternate Rn_Celera

Genomic

  1. AC_000088.1 Alternate Rn_Celera

    Range
    228398..241279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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