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TUB1 alpha-tubulin TUB1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854889, updated on 9-Jul-2017
Gene symbol
TUB1
Gene description
alpha-tubulin TUB1
Primary source
SGD:S000004550
Locus tag
YML085C
Gene type
protein coding
RNA name
alpha-tubulin TUB1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See TUB1 in Map Viewer
Location:
chromosome: XIII
Exon count:
2
Sequence:
Chromosome: XIII; NC_001145.3 (97941..99400, complement)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene cytochrome-b5 reductase Neighboring gene D-arabinono-1,4-lactone oxidase Neighboring gene hypothetical protein Neighboring gene putative cystathionine gamma-synthase

  • Phagosome, organism-specific biosystem (from KEGG)
    Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
  • Phagosome, conserved biosystem (from KEGG)
    Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
homologous chromosome segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
microtubule-based process IEA
Inferred from Electronic Annotation
more info
 
mitotic sister chromatid segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
nuclear migration along microtubule IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic microtubule IC
Inferred by Curator
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
kinetochore microtubule IC
Inferred by Curator
more info
PubMed 
microtubule IEA
Inferred from Electronic Annotation
more info
 
nuclear microtubule IC
Inferred by Curator
more info
PubMed 
nuclear periphery IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
polar microtubule IC
Inferred by Curator
more info
PubMed 
spindle pole body IDA
Inferred from Direct Assay
more info
PubMed 
tubulin complex IDA
Inferred from Direct Assay
more info
PubMed 
tubulin complex IPI
Inferred from Physical Interaction
more info
PubMed 
Names
alpha-tubulin TUB1
NP_013625.1
  • Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    97941..99400 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182444.1NP_013625.1  TPA: alpha-tubulin TUB1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013625.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P09733
    Conserved Domains (2) summary
    PTZ00335
    Location:1446
    PTZ00335; tubulin alpha chain; Provisional
    cd02186
    Location:2436
    alpha_tubulin; The alpha-tubulin family
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