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putative asparagine synthase [ Saccharomyces cerevisiae S288C ]

Gene ID: 854877, updated on 7-Apr-2025

Summary

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Official Full Name
putative asparagine synthase
Primary source
SGD:S000004562
Locus tag
YML096W
See related
AllianceGenome:SGD:S000004562; FungiDB:YML096W; VEuPathDB:YML096W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable asparagine synthase (glutamine-hydrolyzing) activity. Predicted to be involved in asparagine biosynthetic process. Located in cytoplasm. Orthologous to human ASNSD1 (asparagine synthetase domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
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Genomic context

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Location:
chromosome: XIII
Exon count:
1
Sequence:
Chromosome: XIII; NC_001145.3 (79909..81486)

Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Taf13p Neighboring gene guanine nucleotide exchange factor VPS9 Neighboring gene DNA repair protein RAD10 Neighboring gene Gim5p Neighboring gene Utp14p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001145.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Balakrishnan R, et al. Nucleic Acids Res, 2005 Jan 1. PMID 15608219, Free PMC Article
  2. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090, Free PMC Article
  3. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
  4. The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. Bowman S, et al. Nature, 1997 May 29. PMID 9169872
  5. An atlas of chaperone-protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell. Gong Y, et al. Mol Syst Biol, 2009. PMID 19536198, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables asparagine synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within asparagine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative asparagine synthase
NP_013613.1
  • Putative protein with similarity to asparagine synthetases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YML096W is not an essential gene and partially overlaps the verified gene RAD10

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001145.3 Reference assembly

    Range
    79909..81486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182456.1 → NP_013613.1  TPA: putative asparagine synthase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013613.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W0I9, Q04489
    UniProtKB/TrEMBL
    C7GV78, G2WJW1
    Conserved Domains (3) summary
    COG0367
    Location:1 → 513
    AsnB; Asparagine synthetase B (glutamine-hydrolyzing) [Amino acid transport and metabolism]
    cd01991
    Location:232 → 500
    Asn_Synthase_B_C; The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the ...
    cd03766
    Location:1 → 191
    Gn_AT_II_novel; Gn_AT_II_novel. This asparagine synthase-related domain is present in eukaryotes but its function has not yet been determined. The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04489.1

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