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BLZF1 basic leucine zipper nuclear factor 1 [ Homo sapiens (human) ]

Gene ID: 8548, updated on 1-Jun-2020

Summary

Official Symbol
BLZF1provided by HGNC
Official Full Name
basic leucine zipper nuclear factor 1provided by HGNC
Primary source
HGNC:HGNC:1065
See related
Ensembl:ENSG00000117475 MIM:608692
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
JEM1; JEM-1; JEM-1s; GOLGIN-45
Expression
Ubiquitous expression in testis (RPKM 12.9), esophagus (RPKM 10.8) and 25 other tissues See more
Orthologs

Genomic context

See BLZF1 in Genome Data Viewer
Location:
1q24.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (169367879..169396544)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (169337122..169365782)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928596 Neighboring gene Sharpr-MPRA regulatory region 11596 Neighboring gene ATPase Na+/K+ transporting subunit beta 1 Neighboring gene NME/NM23 family member 7 Neighboring gene uncharacterized LOC105371605 Neighboring gene coiled-coil domain containing 181 Neighboring gene solute carrier family 19 member 2 Neighboring gene Sharpr-MPRA regulatory region 2803 Neighboring gene coagulation factor V

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC22497

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding NAS
Non-traceable Author Statement
more info
PubMed 
DNA-binding transcription factor activity NAS
Non-traceable Author Statement
more info
PubMed 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ubiquitin protein ligase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi organization IDA
Inferred from Direct Assay
more info
PubMed 
Golgi to plasma membrane protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi to plasma membrane protein transport IDA
Inferred from Direct Assay
more info
PubMed 
regulation of cell growth NAS
Non-traceable Author Statement
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane TAS
Traceable Author Statement
more info
 
cytoplasm NAS
Non-traceable Author Statement
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
NOT nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
golgin-45
Names
JEM-1short protein
cytoplasmic protein
leucine zipper nuclear factor
p45 basic leucine-zipper nuclear factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320972.1NP_001307901.1  golgin-45 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AF288161, AL356852, AW105286, U79751
    Consensus CDS
    CCDS81397.1
    UniProtKB/Swiss-Prot
    Q9H2G9
    Related
    ENSP00000356781.3, ENST00000367807.7
  2. NM_001320973.2NP_001307902.1  golgin-45 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL021068, CA336342, U79751
    Consensus CDS
    CCDS1278.1
    UniProtKB/Swiss-Prot
    Q9H2G9
    UniProtKB/TrEMBL
    A0A024R921
    Related
    ENSP00000356782.3, ENST00000367808.8
    Conserved Domains (2) summary
    pfam08227
    Location:181226
    DASH_Hsk3; DASH complex subunit Hsk3 like
    cl25732
    Location:132250
    SMC_N; RecF/RecN/SMC N terminal domain
  3. NM_003666.3NP_003657.1  golgin-45 isoform 1

    See identical proteins and their annotated locations for NP_003657.1

    Status: VALIDATED

    Source sequence(s)
    AL021068, AL356852
    Consensus CDS
    CCDS1278.1
    UniProtKB/Swiss-Prot
    Q9H2G9
    UniProtKB/TrEMBL
    A0A024R921
    Related
    ENSP00000327541.2, ENST00000329281.6
    Conserved Domains (2) summary
    pfam08227
    Location:181226
    DASH_Hsk3; DASH complex subunit Hsk3 like
    cl25732
    Location:132250
    SMC_N; RecF/RecN/SMC N terminal domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    169367879..169396544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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