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GVP36 Gvp36p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854770, updated on 7-Jun-2026
Official Symbol
GVP36
Official Full Name
Gvp36p
Primary source
SGD:S000001303
Locus tag
YIL041W
See related
AllianceGenome:SGD:S000001303; FungiDB:YIL041W; VEuPathDB:YIL041W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endocytosis; establishment or maintenance of actin cytoskeleton polarity; and vacuole organization. Located in Golgi membrane. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See GVP36 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (276525..277505)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene cytochrome-b5 reductase Neighboring gene protein kinase PKP1 Neighboring gene Apq12p Neighboring gene Ted1p

Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Proteomic analysis of a nutritional shift-up in Saccharomyces cerevisiae identifies Gvp36 as a BAR-containing protein involved in vesicular traffic and nutritional adaptation. Querin L, et al. J Biol Chem, 2008 Feb 22. PMID 18156177
  2. Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis. Lebesgue N, et al. J Proteome Res, 2017 Feb 3. PMID 28152593
  3. Three members of the yeast N-BAR proteins family form heterogeneous lattices in vivo and interact differentially with two RabGAP proteins. Prigent M, et al. Sci Rep, 2020 Feb 3. PMID 32015451, Free PMC Article
  4. The plasma membrane-enriched fraction proteome response during adaptation to hydrogen peroxide in Saccharomyces cerevisiae. Pedroso N, et al. Free Radic Res, 2012 Oct. PMID 22712517
  5. The 'interactome' of the Knr4/Smi1, a protein implicated in coordinating cell wall synthesis with bud emergence in Saccharomyces cerevisiae. Basmaji F, et al. Mol Genet Genomics, 2006 Mar. PMID 16362369

See all (66) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Atg9, Stp4, and Gvp36 are putative new regulators of sphingolipid homeostasis in Saccharomyces cerevisiae.
    Title: Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis.
  2. Gvp36 represents a novel yeast BAR protein involved in vesicular traffic and in nutritional adaptation
    Title: Proteomic analysis of a nutritional shift-up in Saccharomyces cerevisiae identifies Gvp36 as a BAR-containing protein involved in vesicular traffic and nutritional adaptation.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in establishment or maintenance of actin cytoskeleton polarity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vacuole organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm HDA PubMed 
located_in cytosol HDA PubMed 
Preferred Names
Gvp36p
NP_012223.3
  • BAR domain protein that localizes to early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    276525..277505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179391.3 → NP_012223.3  Gvp36p

    See identical proteins and their annotated locations for NP_012223.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVP1, P40531
    UniProtKB/TrEMBL
    A6ZVM8, B3LTP7, B5VKQ6, C7GVW9, C8ZAK5, G2WGA5, N1P0L9
    Conserved Domains (1) summary
    pfam10455
    Location:27 → 299
    BAR_2; Bin/amphiphysin/Rvs domain for vesicular trafficking
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40531.1

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