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SEC28 coatomer subunit epsilon [ Saccharomyces cerevisiae S288C ]

Gene ID: 854734, updated on 18-Sep-2024

Summary

Official Symbol
SEC28
Official Full Name
coatomer subunit epsilon
Primary source
SGD:S000001338
Locus tag
YIL076W
See related
AllianceGenome:SGD:S000001338; FungiDB:YIL076W; VEuPathDB:YIL076W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ANU2
Summary
Enables promoter-specific chromatin binding activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; late endosome to vacuole transport via multivesicular body sorting pathway; and vesicle coating. Part of COPI vesicle coat. Colocalizes with endosome. Orthologous to human COPE (COPI coat complex subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See SEC28 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (216658..217548)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene threonine--tRNA ligase THS1 Neighboring gene Rci37p Neighboring gene proteasome regulatory particle base subunit RPN2 Neighboring gene phosphoglycerate dehydrogenase SER33

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables promoter-specific chromatin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of COPI vesicle coat IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of COPI vesicle coat IDA
Inferred from Direct Assay
more info
PubMed 
part_of COPI vesicle coat IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in COPI-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
coatomer subunit epsilon
NP_012189.2
  • Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    216658..217548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179426.1NP_012189.2  TPA: coatomer subunit epsilon [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012189.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVK8, P40509
    UniProtKB/TrEMBL
    A6ZVJ7, B3LTS7, C7GKK7, C8ZAG9, G2WG72, N1P2J2
    Conserved Domains (1) summary
    pfam04733
    Location:4293
    Coatomer_E; Coatomer epsilon subunit