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MIP1 DNA-directed DNA polymerase gamma MIP1 [ Saccharomyces cerevisiae S288c ]

Gene ID: 854508, updated on 5-Mar-2017
Gene symbol
MIP1
Gene description
DNA-directed DNA polymerase gamma MIP1
Primary source
SGD:S000005857
Locus tag
YOR330C
Gene type
protein coding
RNA name
DNA-directed DNA polymerase gamma MIP1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
See MIP1 in Map Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (939621..943385, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette multidrug transporter PDR10 Neighboring gene Scd5p Neighboring gene H(+)-transporting V1 sector ATPase subunit E Neighboring gene Mrs2p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
3'-5' exonuclease activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-directed DNA polymerase activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
DNA replication IEA
Inferred from Electronic Annotation
more info
 
mitochondrial DNA replication IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
nucleic acid phosphodiester bond hydrolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
gamma DNA polymerase complex IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
Names
DNA-directed DNA polymerase gamma MIP1
NP_014975.2
  • Mitochondrial DNA polymerase gamma; single subunit of mitochondrial DNA polymerase in yeast, in contrast to metazoan complex of catalytic and accessory subunits; polymorphic in yeast, petites occur more frequently in some lab strains; human ortholog POLG complements yeast mip1 mutant; mutations in human POLG associated with Alpers-Huttenlocher syndrome (AHS), progressive external ophthalmoplegia (PEO), parkinsonism, other mitochondrial diseases

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    939621..943385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183750.1NP_014975.2  TPA: DNA-directed DNA polymerase gamma MIP1 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_014975.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P15801
    Conserved Domains (2) summary
    cd08641
    Location:581960
    DNA_pol_gammaA; Pol gammaA is a family A polymerase that is responsible for DNA replication and repair in mitochondria
    COG0749
    Location:6481254
    PolA; DNA polymerase I - 3'-5' exonuclease and polymerase domains [Replication, recombination and repair]
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