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RPN8 proteasome regulatory particle lid subunit RPN8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854435, updated on 6-Oct-2020

Summary

Gene symbol
RPN8
Gene description
proteasome regulatory particle lid subunit RPN8
Primary source
SGD:S000005787
Locus tag
YOR261C
Gene type
protein coding
RNA name
proteasome regulatory particle lid subunit RPN8
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See RPN8 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (815915..816931, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene proteasome regulatory particle base subunit RPT4 Neighboring gene translation initiation factor eIF2B subunit gamma Neighboring gene putative GTPase GPN2 Neighboring gene Dse3p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RPN8 gene: The RPN8 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
isopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin-dependent protein catabolic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
proteasome complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome complex IEA
Inferred from Electronic Annotation
more info
 
proteasome regulatory particle IEA
Inferred from Electronic Annotation
more info
 
proteasome regulatory particle, lid subcomplex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome storage granule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
proteasome regulatory particle lid subunit RPN8
NP_014904.3
  • Essential non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    815915..816931 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183680.3NP_014904.3  TPA: proteasome regulatory particle lid subunit RPN8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014904.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q08723
    Conserved Domains (1) summary
    cd08062
    Location:6303
    MPN_RPN7_8; Mpr1p, Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity, found in 19S proteasomal subunits Rpn7 and Rpn8
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