Format

Send to:

Choose Destination

SEC63 protein-transporting protein SEC63 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854428, updated on 6-Feb-2018
Gene symbol
SEC63
Gene description
protein-transporting protein SEC63
Primary source
SGD:S000005780
Locus tag
YOR254C
Gene type
protein coding
RNA name
protein-transporting protein SEC63
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PTL1
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (805032..807023, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Tma16p Neighboring gene peptide alpha-N-acetyltransferase subunit NAT5 Neighboring gene Osw1p Neighboring gene putative zinc metalloprotease

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
protein transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
protein transporter activity IEA
Inferred from Electronic Annotation
more info
 
protein transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
SRP-dependent cotranslational protein targeting to membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
cytosol to ER transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
posttranslational protein targeting to endoplasmic reticulum membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
posttranslational protein targeting to membrane, translocation IDA
Inferred from Direct Assay
more info
PubMed 
posttranslational protein targeting to membrane, translocation IEA
Inferred from Electronic Annotation
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Sec62/Sec63 complex IPI
Inferred from Physical Interaction
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane ISM
Inferred from Sequence Model
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
nuclear inner membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
protein-transporting protein SEC63
NP_014897.1
  • Essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec62p, Sec66p, and Sec72p

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    805032..807023 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183673.1NP_014897.1  TPA: protein-transporting protein SEC63 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014897.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P14906
    Conserved Domains (1) summary
    COG5407
    Location:1658
    SEC63; Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport]
Support Center