RET1 DNA-directed RNA polymerase III core subunit RET1 [Saccharomyces cerevisiae S288C] - Gene

Summary

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Gene symbol: RET1
Gene description: DNA-directed RNA polymerase III core subunit RET1
Primary source: SGD:S000005733
Locus tag: YOR207C
Gene type: protein coding
RNA name: DNA-directed RNA polymerase III core subunit RET1
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: PDS2; RPC128; RPC2

Genomic context

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See RET1 in Genome Data Viewer

Location:: chromosome: XV

Exon count:: 1

Sequence:: Chromosome: XV; NC_001147.6 (730008..733457, complement)

Chromosome XV - NC_001147.6 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Yeast Bud27 modulates the biogenesis of Rpc128 and Rpc160 subunits and the assembly of RNA polymerase III.
Title: Yeast Bud27 modulates the biogenesis of Rpc128 and Rpc160 subunits and the assembly of RNA polymerase III.
the properties of the corresponding RNAPII (Rpb2-832GYNQED837) and RNAPIII (Rpc128-764GYDIED769) loops by a local mutagenesis of their invariant carboxyl acids.
Title: Crucial role of a dicarboxylic motif in the catalytic center of yeast RNA polymerases.

Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Homologs of the RET1 gene: The RET1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function	Evidence Code	Pubs
DNA binding	IEA Inferred from Electronic Annotation more info
contributes_to DNA-directed 5'-3' RNA polymerase activity	IBA Inferred from Biological aspect of Ancestor more info	PubMed
DNA-directed 5'-3' RNA polymerase activity	IEA Inferred from Electronic Annotation more info
contributes_to RNA polymerase III activity	IDA Inferred from Direct Assay more info	PubMed
metal ion binding	IEA Inferred from Electronic Annotation more info
nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
ribonucleoside binding	IEA Inferred from Electronic Annotation more info
transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
tRNA transcription by RNA polymerase III	IDA Inferred from Direct Assay more info	PubMed
tRNA transcription by RNA polymerase III	IGI Inferred from Genetic Interaction more info	PubMed
transcription, DNA-templated	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
RNA polymerase III complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
RNA polymerase III complex	IDA Inferred from Direct Assay more info	PubMed
nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: DNA-directed RNA polymerase III core subunit RET1

NP_014850.1

EC 2.7.7.6

Second-largest subunit of RNA polymerase III; RNA polymerase III is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001147.6 Reference assembly

Range

730008..733457 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001183626.1 → NP_014850.1 TPA: DNA-directed RNA polymerase III core subunit RET1 [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_014850.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P22276

Conserved Domains (1) summary

COG0085
Location:26 → 1147

RpoB; DNA-directed RNA polymerase, beta subunit/140 kD subunit [Transcription]

Nucleotide		Protein
Heading	Accession and Version	Protein

Protein Accession	Links
Protein Accession	GenPept Link	UniProtKB Link
6CNB_B.1
6CNC_B.1
6CND_B.1
6CNF_B.1
6EU0_B.1
6EU1_B.1
6EU2_B.1
6EU3_B.1
6F40_B.1
6F41_B.1
6F42_B.1
6F44_B.1
6TUT_B.1
P22276.2