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MRM1 Mrm1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854376, updated on 7-Jun-2026
Official Symbol
MRM1
Official Full Name
Mrm1p
Primary source
SGD:S000005727
Locus tag
YOR201C
See related
AllianceGenome:SGD:S000005727; FungiDB:YOR201C; VEuPathDB:YOR201C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PET56
Summary
Enables rRNA (guanine-N1-)-methyltransferase activity. Involved in rRNA modification. Located in mitochondrion. Orthologous to human MRM1 (mitochondrial rRNA methyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
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See MRM1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (720470..721708, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ca(2+)-dependent cysteine protease MCA1 Neighboring gene Bfr1p Neighboring gene imidazoleglycerol-phosphate dehydratase HIS3 Neighboring gene DEAD-box ATP-dependent RNA helicase DED1

Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Poly(dA).poly(dT) rich sequences are not sufficient to exclude nucleosome formation in a constitutive yeast promoter. Losa R, et al. Nucleic Acids Res, 1990 Jun 25. PMID 2194162, Free PMC Article
  2. The role of nucleotide modifications in the yeast mitochondrial ribosome. Sirum-Connolly K, et al. Nucleic Acids Symp Ser, 1995. PMID 8643404
  3. Functional requirement of a site-specific ribose methylation in ribosomal RNA. Sirum-Connolly K, et al. Science, 1993 Dec 17. PMID 8266080
  4. Transcription through the yeast origin of replication ARS1 ends at the ABFI binding site and affects extrachromosomal maintenance of minichromosomes. Tanaka S, et al. Nucleic Acids Res, 1994 Sep 25. PMID 7937110, Free PMC Article
  5. Constitutive and inducible Saccharomyces cerevisiae promoters: evidence for two distinct molecular mechanisms. Struhl K. Mol Cell Biol, 1986 Nov. PMID 3540601, Free PMC Article

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA (guanine) methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA (guanine-N1-)-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA modification IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA modification IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion EXP
Inferred from Experiment
more info
 PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Mrm1p
NP_014844.3
  • Ribose methyltransferase; modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    720470..721708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183620.3 → NP_014844.3  Mrm1p

    See identical proteins and their annotated locations for NP_014844.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2Q8, P25270
    UniProtKB/TrEMBL
    A6ZP45, B5VS84, C7GWI0, N1NX53
    Conserved Domains (1) summary
    TIGR00186
    Location:123 → 412
    rRNA_methyl_3; rRNA methylase, putative, group 3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25270.2

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