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BFR1 Bfr1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854373, updated on 17-May-2024

Summary

Gene symbol
BFR1
Gene description
Bfr1p
Primary source
FungiDB:YOR198C
Locus tag
YOR198C
See related
SGD:S000005724; AllianceGenome:SGD:S000005724; VEuPathDB:YOR198C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA binding activity. Involved in several processes, including protein O-linked mannosylation; protein insertion into ER membrane; and regulation of mitotic nuclear division. Located in endoplasmic reticulum and nuclear outer membrane-endoplasmic reticulum membrane network. Part of polysome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See BFR1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (718653..720065, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene putative lipoate synthase Neighboring gene Ca(2+)-dependent cysteine protease MCA1 Neighboring gene Mrm1p Neighboring gene imidazoleglycerol-phosphate dehydratase HIS3

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables mRNA binding HDA PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mRNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum IMP
Inferred from Mutant Phenotype
more info
PubMed 
is_active_in nuclear outer membrane-endoplasmic reticulum membrane network IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear outer membrane-endoplasmic reticulum membrane network IDA
Inferred from Direct Assay
more info
PubMed 
part_of ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ribonucleoprotein complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
Bfr1p
NP_014841.1
  • Component of mRNP complexes associated with polyribosomes; involved in localization of mRNAs to P bodies; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    718653..720065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183617.1NP_014841.1  TPA: Bfr1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014841.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W2Q7, P38934
    UniProtKB/TrEMBL
    A0A6A5Q477, A6ZP44, B5VS83, C7GWI1, C8ZGV7, G2WN73, N1P3E6
    Conserved Domains (1) summary
    COG1196
    Location:3277
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]