U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

RKI1 ribose-5-phosphate isomerase RKI1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854262, updated on 5-Jul-2025
Official Symbol
RKI1
Official Full Name
ribose-5-phosphate isomerase RKI1
Primary source
SGD:S000005621
Locus tag
YOR095C
See related
AllianceGenome:SGD:S000005621; FungiDB:YOR095C; VEuPathDB:YOR095C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables ribose-5-phosphate isomerase activity. Involved in pentose-phosphate shunt and pyridoxine biosynthetic process. Located in cytoplasm and nucleus. Orthologous to human RPIA (ribose 5-phosphate isomerase A). [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table
See RKI1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (503552..504328, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Cmr2p Neighboring gene Arf family GTPase ARF3 Neighboring gene 40S ribosomal protein eS7 RPS7A Neighboring gene uncharacterized protein

Genomic Sequence:
NC_001147.6
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables ribose-5-phosphate isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ribose-5-phosphate isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables ribose-5-phosphate isomerase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in D-ribose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in pentose-phosphate shunt IEA
Inferred from Electronic Annotation
more info
 
involved_in pentose-phosphate shunt IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in pentose-phosphate shunt, non-oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in pentose-phosphate shunt, non-oxidative branch IEA
Inferred from Electronic Annotation
more info
 
involved_in pyridoxine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus HDA PubMed 
Preferred Names
ribose-5-phosphate isomerase RKI1
NP_014738.1
  • Ribose-5-phosphate ketol-isomerase; catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    503552..504328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183514.1NP_014738.1  TPA: ribose-5-phosphate isomerase RKI1

    See identical proteins and their annotated locations for NP_014738.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZNU5, D6W2F6, Q12189
    UniProtKB/TrEMBL
    B3LJE1, C7GMN9, C8ZI56, G2WMX2, N1NWX9
    Conserved Domains (1) summary
    TIGR00021
    Location:22253
    rpiA; ribose 5-phosphate isomerase