Format

Send to:

Choose Destination

HIR2 Hir2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854203, updated on 4-Aug-2021

Summary

Gene symbol
HIR2
Gene description
Hir2p
Primary source
SGD:S000005564
Locus tag
YOR038C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
SPT1
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See HIR2 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (402761..405388, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene SNAP receptor PEP12 Neighboring gene oxidoreductase Neighboring gene casein kinase 2 regulatory subunit CKB2 Neighboring gene hydroxyacylglutathione hydrolase GLO4

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to nucleosome binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of HIR complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of HIR complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of HIR complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Hir2p
NP_014681.1
  • Subunit of HIR nucleosome assembly complex; involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p; relocalizes to the cytosol in response to hypoxia

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    402761..405388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183457.1NP_014681.1  TPA: Hir2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014681.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P32480
    Conserved Domains (3) summary
    sd00039
    Location:123163
    7WD40; WD40 repeat [structural motif]
    pfam07569
    Location:581816
    Hira; TUP1-like enhancer of split
    cl29593
    Location:172350
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Support Center