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DFG16 Dfg16p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854195, updated on 3-May-2025
Official Symbol
DFG16
Official Full Name
Dfg16p
Primary source
SGD:S000005556
Locus tag
YOR030W
See related
AllianceGenome:SGD:S000005556; FungiDB:YOR030W; VEuPathDB:YOR030W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ECM41; ZRG12
Summary
Involved in protein processing and pseudohyphal growth. Located in plasma membrane. [provided by Alliance of Genome Resources, May 2025]
Orthologs
all
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See DFG16 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (386825..388684)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Cin5p Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene Hms1p

Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. N-glycosylation of Rim21 at an Unconventional Site Fine-tunes Its Behavior in the Plasma Membrane. Obara K, et al. Cell Struct Funct, 2020 Jan 11. PMID 31787665, Free PMC Article
  2. The C-terminal Cytosolic Region of Rim21 Senses Alterations in Plasma Membrane Lipid Composition: INSIGHTS INTO SENSING MECHANISMS FOR PLASMA MEMBRANE LIPID ASYMMETRY. Nishino K, et al. J Biol Chem, 2015 Dec 25. PMID 26527678, Free PMC Article
  3. Membrane protein Rim21 plays a central role in sensing ambient pH in Saccharomyces cerevisiae. Obara K, et al. J Biol Chem, 2012 Nov 9. PMID 23019326, Free PMC Article
  4. Relationship of DFG16 to the Rim101p pH response pathway in Saccharomyces cerevisiae and Candida albicans. Barwell KJ, et al. Eukaryot Cell, 2005 May. PMID 15879523, Free PMC Article
  5. Identification of a complex genetic network underlying Saccharomyces cerevisiae colony morphology. Voordeckers K, et al. Mol Microbiol, 2012 Oct. PMID 22882838, Free PMC Article

See all (54) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An S. cerevisiae dfg16Delta mutant expresses Rim101p-repressed genes at elevated levels.
    Title: Relationship of DFG16 to the Rim101p pH response pathway in Saccharomyces cerevisiae and Candida albicans.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to pH IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
Dfg16p
NP_014673.1
  • Probable multiple transmembrane protein; involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; is glycosylated and phosphorylated; interacts with Rim21p and Rim9p in the plasma membrane to form a pH-sensing complex in the Rim101 pathway and is required to maintain Rim21p levels; required for accumulation of processed Rim101p

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    386825..388684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183449.1 → NP_014673.1  TPA: Dfg16p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014673.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W295, Q99234
    UniProtKB/TrEMBL
    A6ZNN3, B3LJ83, C7GLF9, C8ZHZ0, G2WMR0, N1NVR0
    Conserved Domains (1) summary
    pfam08733
    Location:86 → 459
    PalH; PalH/RIM21
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99234.1

Gene LinkOut

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