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BUB3 Bub3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854191, updated on 5-Sep-2021

Summary

Gene symbol
BUB3
Gene description
Bub3p
Primary source
SGD:S000005552
Locus tag
YOR026W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
PAC9
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Genomic context

See BUB3 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (379781..380806)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ahc1p Neighboring gene NAD-dependent histone deacetylase HST3 Neighboring gene Hsp90 cochaperone STI1 Neighboring gene Cin5p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ubiquitin binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic DNA integrity checkpoint signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in mitotic spindle assembly checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of protein autoubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of bub1-bub3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
part_of mitotic checkpoint complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of mitotic checkpoint complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of mitotic checkpoint complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Bub3p
NP_014669.1
  • Kinetochore checkpoint WD40 repeat protein; localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p; functions at kinetochore to activate APC/C-Cdc20p for normal mitotic progression

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    379781..380806
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183445.1NP_014669.1  TPA: Bub3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014669.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P26449
    Conserved Domains (2) summary
    COG2319
    Location:2317
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:1455
    7WD40; WD40 repeat [structural motif]
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