U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

AHC1 Ahc1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854188, updated on 19-Nov-2025
Official Symbol
AHC1
Official Full Name
Ahc1p
Primary source
SGD:S000005549
Locus tag
YOR023C
See related
AllianceGenome:SGD:S000005549; FungiDB:YOR023C; VEuPathDB:YOR023C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to histone acetyltransferase activity. Involved in replication-born double-strand break repair via sister chromatid exchange. Part of ADA complex. [provided by Alliance of Genome Resources, Jul 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table
See AHC1 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (376012..377712, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene protein-arginine N-methyltransferase SFM1 Neighboring gene putative carboxylic ester hydrolase Neighboring gene NAD-dependent histone deacetylase HST3 Neighboring gene Bub3p

Genomic Sequence:
NC_001147.6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium. Ricci AR, et al. Mol Cell Biol, 2002 Jun. PMID 12024017, Free PMC Article
  2. The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae. Eberharter A, et al. Mol Cell Biol, 1999 Oct. PMID 10490601, Free PMC Article
  3. The Aurora-B-dependent NoCut checkpoint prevents damage of anaphase bridges after DNA replication stress. Amaral N, et al. Nat Cell Biol, 2016 May. PMID 27111841
  4. N-terminal domain of nuclear IL-1α shows structural similarity to the C-terminal domain of Snf1 and binds to the HAT/core module of the SAGA complex. Zamostna B, et al. PLoS One, 2012. PMID 22879895, Free PMC Article
  5. TopBP1/Dpb11 binds DNA anaphase bridges to prevent genome instability. Germann SM, et al. J Cell Biol, 2014 Jan 6. PMID 24379413, Free PMC Article

See all (58) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Chromatin regulator Ahc1p co-regulates nitrogen metabolism via interactions with multiple transcription factors in Saccharomyces cerevisiae.
    Title: Chromatin regulator Ahc1p co-regulates nitrogen metabolism via interactions with multiple transcription factors in Saccharomyces cerevisiae.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to histone acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in replication-born double-strand break repair via sister chromatid exchange IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of ADA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ADA complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus NAS
Non-traceable Author Statement
more info
 PubMed 
Preferred Names
Ahc1p
NP_014666.1
  • Subunit of the Ada histone acetyltransferase complex; required for structural integrity of the complex; Ahc2p and Ahc1p are unique to the ADA complex and not shared with the related SAGA and SLIK complexes; Ahc2p may tether Ahc1p to the complex

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    376012..377712 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183442.1 → NP_014666.1  TPA: Ahc1p

    See identical proteins and their annotated locations for NP_014666.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W290, Q12433
    UniProtKB/TrEMBL
    C7GLF4, G2WMQ5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12433.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools