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RFC4 replication factor C subunit 4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 854059, updated on 9-Sep-2018

Summary

Gene symbol
RFC4
Gene description
replication factor C subunit 4
Primary source
SGD:S000005454
Locus tag
YOL094C
Gene type
protein coding
RNA name
replication factor C subunit 4
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces

Genomic context

See RFC4 in Genome Data Viewer
Location:
chromosome: XV
Exon count:
1
Sequence:
Chromosome: XV; NC_001147.6 (141584..142555, complement)

Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene hexaprenyldihydroxybenzoate methyltransferase Neighboring gene ATP-dependent 3'-5' DNA helicase Neighboring gene tRNA (guanine(9)-N(1))-methyltransferase Neighboring gene cationic amino acid transporter

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to DNA clamp loader activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to DNA clamp loader activity IDA
Inferred from Direct Assay
more info
PubMed 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA replication IEA
Inferred from Electronic Annotation
more info
 
DNA-dependent DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
leading strand elongation IDA
Inferred from Direct Assay
more info
PubMed 
mismatch repair TAS
Traceable Author Statement
more info
PubMed 
sister chromatid cohesion IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
Ctf18 RFC-like complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Ctf18 RFC-like complex IPI
Inferred from Physical Interaction
more info
PubMed 
DNA replication factor C complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA replication factor C complex IDA
Inferred from Direct Assay
more info
PubMed 
DNA replication factor C complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Elg1 RFC-like complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Elg1 RFC-like complex IPI
Inferred from Physical Interaction
more info
PubMed 
Rad17 RFC-like complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Rad17 RFC-like complex IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
replication factor C subunit 4
NP_014547.1
  • Subunit of heteropentameric Replication factor C (RF-C); which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon; relocalizes to the cytosol in response to hypoxia

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001147.6 Reference assembly

    Range
    141584..142555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183348.1NP_014547.1  TPA: replication factor C subunit 4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014547.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40339
    Conserved Domains (1) summary
    cl25702
    Location:9323
    Rad17; Rad17 cell cycle checkpoint protein
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